![]() Villous atrophy was found in more than 50% of the patients who were diagnosed with celiac disease. Anti-tTG antibodies have more diagnostic value than duodenal endoscopy. On endoscopic evaluation, out of 50 positive anti-tTG antibodies cases, 24 had normal mucosa while partial villous atrophy observed in 15 (30%) cases and total villous atrophy observed in 11 cases (22%).Ĭonclusions: Celiac disease was more prevalent in young females and patients usually presents with history of chronic diarrhea. The most common symptoms were presence of chronic diarrhea (74%, n=37) followed by abdominal pain (52%, n=26), nausea & vomiting (34%, n=17), and least common was presence of constipation (2%, n=1). Young population (31.14☖.07 years) with females predominance (72%, n=36) were more common than males. Diagnostic accuracy of endoscopy was 34.6%. and specificity for the diagnosis of celiac disease110 (Table 35-2). Results: A total of 50 patients were recruited for final analysis. Serological tests have acquired great importance in. Endoscopic evaluation of duodenum was performed in all positive cases. Celiac disease was confirmed based on positive anti-tTG antibodies. Patients who did not willing to participate, patients already taking gluten diet for more than 3 months, patients with other causes of chronic diarrhea and alternate diagnosis like thyrotoxicosis, whipple’s disease, giardiasis, patients with drug induced diarrhea, patients in whom we cannot perform endoscopy, pregnant women, and patients already diagnosed cases of celiac disease were excluded from this study. Methods: All the suspected cases (based on their clinical manifestations) of celiac disease were initially recruited having age >14 years and <40 years of both gender. Patients present with diarrhea, weight loss, steatorrhea, or malnutrition syndromes such as anemia and diminished bone mass due to deficiencies of important nutrients (iron, folate, calcium, and fat-soluble vitamins) 3. serology findings of patients with suspected celiac disease Objective: To determine the association between endoscopic findings vs. ![]()
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